Ascending & Sensory Systems

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What is the process of transduction? Stimulus changes the membrane permeability for specific ions->depolarization->generator potential->if threshold is met, the potential is generated to first node of Ranvier->if large enough, action potential to CNS.  
What is the general classification of sensory receptors? Exteroreceptive, proprioceptive, and interoreceptive.  
What type of receptor responds to stimuli from the external environment? Exteroreceptive.  
What type of receptor responds to positions of the body in space? Proprioceptive.  
What type of receptor responds to internal changes wuch as O2 or CO2 levels? Interoreceptive.  
What types of receptors are classified based on the sensory stimuli they detect? Mechanoreceptors, thermoreceptors, nociceptors, electromagnetic, and chemoreceptors.  
What receptor responds to tapping, touch, vibration, and stretch? Mechanoreceptors.  
What are the two types of mechanoreceptors? Tactile sense and position sense.  
What receptor responds to temperature changes? Thermoreceptors.  
What receptor is also known as a pain receptor or free nerve ending? Nociceptors.  
What receptor responds to any stimulus at a magnitude to cause damage? Nociceptors.  
What receptor responds to light energy (rods & cones)? Electromagnetic.  
What receptor is also known as an interoreceptor? Chemoreceptors.  
What receptor responds to changes in chemicals such as glucose, oxygen, and carbon dioxide? Chemoreceptors.  
What are the two types of receptors that are based on their adaptation speed? Slowly adapting (tonic) and rapidly adapting (phasic) receptors.  
What is the purpose of slowly adapting (tonic) receptors? To transmit information to the brain as long as the stimulus is present, keeps the brain continually updated on the status of the body.  
What are two examples of slowly adapting (tonic) receptors? Muscle spindles and pain receptors.  
What is the purpose of rapidly adapting (phasic) receptors? They fire and then fire again only when the stimulus changes.  
What is an example of rapidly adapting (phasic) receptors? Hair end organs.  
What are the five types of tactile mechanoreceptors? Meissner’s Corpuscles, Merkel’s Cell Disc, Pacinian Corpuscles, Ruffini Endings, and Peritrichial Plexi (hair end organ).  
What is the sense of static position and joint angulation called? Proprioception.  
What is the sense of movement called? Kinesthesia.  
Where are Meissner’s Corpuscles found? Non-hairy (glabrous) skin, smallest receptive fields are in the fingerpads and the fields increase in size as you move more proximally in the hand.  
What is the purpose of Meissner’s Corpuscles? Discrimination of texture and objects, sensitive to movement of light objects over the surface of the skin, low frequency vibration, stereognosis.  
Where are Merkel’s Cell Discs found? Smooth and hairy skin, often grouped together in a single receptor called the Iggo dome receptor, found more densely in the distal phalanx.  
What is the purpose of Merkel’s Cell Discs? Fire during sustained indentation, discriminative two-point touch, “bull’s eye” area of sensitivity surrounded by an area of less sensitivity.  
Where are Pacinian corpuscles found? Deep within the dermis.  
What is the purpose of Pacinian corpuscles? Cushioning fluid between the layers surrounding the nerve fiber equalize the pressure stimulus removing it from the afferent fiber at the core, sensitive to high frequency vibration, tickle.  
Where are Ruffini endings found? In the dermis and joints, hook onto collagen fibers, uniformly distributed throughout the hand.  
What is the purpose of Ruffini endings? Important for continuous touch and pressure signals, respond to skin being stretched (significant reduction in finger dexterity when hand is edematous).  
Where are Peritrichial Plexi found? At hair ends.  
What is the purpose of Peritrichial Plexi? Alert and orient to the environment.  

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