Drugs for bugs
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| Aminoglycoside - Streptomycin | M. tuberculosum | |
| Aminoglycoside - Gentamycin / Tobramycin | Good for GNRs. Not for anaerobes | |
| Aminoglycoside - Gentamycin / Tobramycin | Typically used for bloodstream infections and UTI | |
| Tobramycin | Strong affinity for Pseudomonas | |
| Aminoglycoside - Gentamycin / Tobramycin | Workhorses. Use on aerobic Gram Neg Rods | |
| Aminoglycosides - Streptomycin | Use only in combination | |
| Aminoglycosides - Streptomycin | Used with Ampicillin for Enterococcus | |
| Aminoglycosides - **Amikacin** | Reserved for Resistant GNRs | |
| Oxazolidinodes - Linezolid (Zivox) | Inhibits 50S by binding 30S subunit | |
| Oxazolidinodes - Linezolid (Zivox) | PO/IV, Gram+, Good for resistant bugs | |
| Oxazolidinodes - Linezolid (Zivox) | Resistant Pseudomonas & Staph aureus & lung infex | |
| Oxazolidinodes - Linezolid (Zivox) | S/E Thrombocytopenia, leukopenia, anemia | |
| Oxazolidinodes - Linezolid (Zivox) | S/E Neuropathy, mitochondrial toxicity | |
| Tetracyclines - Doxy-, Mino-, Tige- (IV/PO) | Alter A site of 30S preventing tRNA binding | |
| Tetracyclines - Doxy-, Mino-, Tige- (IV/PO) | Long lasting, reversible | |
| Tetracyclines - Doxy-, Mino-, Tige- (IV/PO) | Binds metals (Ca), captures photons | |
| Tetracyclines - Doxy-, Mino-, Tige- (IV/PO) | Broad spectrum: Gram+/- & anaerobes | |
| Tetracycline (PO) | Broad spectrum, QID, lots of resistance | |
| Doxycycline(IV/PO) | Broad Spectrum, BID, for intracellular bugs | |
| Minocycline (IV/PO) | Broad Spectrum, BID, good for S. aureus (intracellular) |
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