Olfaction and Taste

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Cards

Explain the concept of the nose brain (Rhinencephalon). Forms a complex system of neural circuits for the sense of smell.  
What is the rhinencephalon linked with? The neocortex, the hypothalamus, thalamus, and reticular formation.  
What are the subdivisions of the rhinencephalon? Archicortex, paleocortex, and neocortex.  
What is the archicortex associated with? The hippocampus.  
What is the paleocortex associated with? The olfactory response.  
What is the neocortex associated with? New cortex.  
What are the factors that can cause anosmia either permanently or temporarily Head injury.  
Explain how sense of smell is involved in the limbic system. The connection to the hypothalamus is responsible for salivation, gastric secretions, peristalsis, social interaction, and reproductive behavior, the connection from the amygdala to the thalamus and entrorhinal cortex plays a role in memory, reproductive, and defense behaviors.  
What is the pathway from the amygdala to the hypothalamus? Through the stria terminalis to the septal nucleus to the hypothalamus.  
Explain the pathway for the sense of smell. Olfactory nerve travels through the cribiform plate of the ethmoid bone, enters the olfactory bulb, axons terminate in the glomeruli found in the bulb.  
What is in the glomeruli? The mitral and tuft neurons, their axons become the olfactory tract.  
Describe the olfactory tract. Divides into the lateral and medial olfactory striae (tracts), lateral is uncrossed, medial is crossed (anterior commissure).  
What are the key areas of synapse? Anterior olfactory nucleus, olfactory tubercle, piriform cortex, medial cortex of the amygdala, entrorhinal cortex.  
Where do the olfactory tubercle and piriform cortex send the signal? In the stria medullaris to the medial dorsal nucleus of the thalamus and then to the orbital frontal cortex.  
Explain the concept of the uncinate fit. Olfactory or gustatory hallucinations (unpleasant), and convulsions.  
Define rhinorrhea. Watery discharge from the nose, possibly CSF leakage.  
Define anosmia. A complete loss of smell.  
Where are sweet and salty tastes found? On the tip of the tongue.  
Where are sour tastes found? On the sides of the tongue.  
Where are bitter tastes found? The back of the tongue and soft palate.  
Taste buds from the anterior 2/3 of the tongue are carried by which cranial nerve? Facial CN VII, via the chorda tympani nerve.  
Taste buds from the posterior 1/3 of the tongue are carried by which cranial nerve? Glossopharangeal CN IX.  
Taste buds from the epiglottis are carried by which cranial nerve? Vagus CN X.  
Explain the pathway for the first order neuron in the sense of taste. First order neurons synapse in the solitary nucleus, CN VII = rostral portion, CN IX & X = caudal portion.  
Explain the pathway for the second order neuron in the sense of taste. Sent to the ventral posterior medial nucleus of the thalamus.  
Explain the pathway for the third order neuron in the sense of taste. Postcentral gyrus of the parietal cortex into the lateral fissure/insular area (area 43).  
Define ageusia. Complete loss of the sense of taste.  
Defined hypoguesia. Partial loss of taste.  
Define dysgeusia. Persistent, unpleasant taste.  
Define parageusia. Abnormal perception of taste.  
Defined gustatory hallucinations. Disagreeable, happens before or during a seizure.  

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